In 2006, she and her son Julian Lennon attended the Las Vegas premiere of the Cirque du Soleil production of Love whose theme is the music of the Beatles. Over the years she staged several auctions of memorabilia associated with her life with John Lennon. In 2005, she published a more intimate biography, John. She published a book of memoirs, A Twist of Lennon, in 1978, and later was married to Noel Charles, a night club owner, from 2002 until his death in 2013. After her divorce from Twist, she changed her name back to 'Lennon' bydeed poll and met Jim Christie, her partner for 17 years. In 1976, she married John Twist, an engineer from Lancashire, but divorced him in 1983. She married Italian hotelier Roberto Bassanini in 1970, divorcing him in 1973. In 1968, John left her for Yoko Ono the couple's divorce was legally granted on 8 November 1968.

In 1964, they lived at Kenwood in Weybridge, where she kept house and participated with her husband in a London-based social life. After Powell became pregnant, she and John were married on 23 August 1962 at the Mount Pleasantregister office in Liverpool.

When John was performing in Hamburg with the Beatles, she rented his bedroom from his aunt and legal guardian, Mimi Smith. John Lennon also attended the college a meeting with Lennon in a calligraphy class led to their relationship. At the age of 12, she was accepted into the Junior Art School, and was later enrolled in the Liverpool College of Art. She grew up in the middle-class section of Hoylake, on the Wirral Peninsula in North West England.

Yoko ono and cynthia lennon